Center for Neuroscience
Dept. of Neurobiology, Physiology, and Behavior
In the Usrey Lab, I study thalamocortical circuits of the visual system. Specifically, I am interested in how corticogeniculate feedback modulates visual processing in the LGN. By studying feedback’s physiological and anatomical characteristics, I can identify the functional properties of feedback and characterize how the thalamus and cortex dynamically interact to influence visual processing. Because feedback pathways are particularly sensitive to anesthesia, I conduct my experiments in alert animals and manipulate feedback using optogenetics while recording simultaneously the visual responses of individual and small ensembles of LGN neurons. Acute experiments utilizing anterograde and retrograde tracers indicate the anatomical properties of the feedback system.
I am also assisting the collection data exploring the pulvinar in the thalamus as either a driving and/or modulatory input between V1 and V2.
- Sanchez AN & Usrey WM. (in preparation). Eye to Brain: Parallel Visual Pathways In P. Martin (Eds.), The Senses: A Comprehensive Reference, 2nd Edition. Elsevier.
- Society for Neuroscience (2019) Poster: Effects of amplitude-modulated signal-in-noise auditory stimuli on the firing rates of auditory cortical neurons in an awake macaque monkey. Sanchez AN, Cazabon DB, Bormann B, Neverkovek K, Cheung KB, Recanzone GH.
- Society for Neuroscience (2019) Poster Abstract: Intracortical microstimulation of sensorimotor cortex in short-tailed opossum (Monodelphis domestica): New insights into the evolution of motor cortex in mammals. Halley AC, Baldwin MKL, Englund M, Sanchez A, Krubitzer L.